Examinando por Materia "Nanotechnology"

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Promising physicochemical technologies for poultry slaughterhouse wastewater treatment: A critical review
(ELSEVIER, 2021-02-06) Terán Hilares, Ruly; Atoche Garay, Diego Fernando; Pinto Pagaza, Daniel A.; Ajaz Ahmed, Muhammed; Colina Andrade, Gilberto J.; Santos Peláez, Julio César
Poultry slaughterhouse wastewater (PSWW) is a serious concern mainly due to the huge generation and associated characteristics of high organic matter and nutrients (N, P) that this contains. Therefore, an understanding development and adaption of an apposite wastewater treatment option focused specifically on PSWW is an absolute need. Recently, innovative physicochemical-based technologies, such as; acid precipitation, electrochemical advanced oxidation, cavitation-based processes and even nanotechnology assisted processes have been reported as prominent alternatives for wastewater treatment. In this article, we performed a systematic literature review and a comprehensive discussion about these technologies, aiming to show them as alternatives for PSWW treatment. Among all discussed technologies, hydrodynamic cavitation (HC) was observed as an interesting possibility that can be implemented in combination with other processes for efficient pollutant degradation. It could be, e.g., associated with nanoparticles, nanocomposites and nanobubbles, which are also an interesting alternative to be associated with membranes, generating turbulence, and mitigating problems as fouling. Finally, the wide knowledge about such treatment technologies can offer a more cost-effective PSWW management, thus, allowing an adequate implementation from technical and economical viewpoints.
Vaccination with formulation of nanoparticles loaded with Leishmania amazonensis antigens confers protection against experimental visceral Leishmaniasis in hamster
(MDPI, 2023-01-02) Maia Gonçalves, Ana Alice; Ottino, Jennifer; Costa Leite, Jaqueline; Aparecida Resende, Lucilene; Melo Júnior, Otoni Alves; Silveira, Patrícia; Santos Cardoso, Mariana; Toshio Fujiwara, Ricardo; Lacerda Bueno, Lilian; Lima Santos, Renato; Furtado de Carvalho, Tatiane; Martins Garcia, Giani; de Oliveira Paes, Paulo Ricardo; Sobreira Galdino, Alexsandro; Chávez Fumagalli, Miguel Angel; Martins Melo, Marília; Silveira Lemos, Denise; Martins Filho, Olindo Assis; Ornelas Dutra, Walderez; Furtado Mosqueira, Vanessa Carla; Cordeiro Giunchetti, Rodolfo
Visceral leishmaniasis (VL) is a fatal disease caused by the protozoa Leishmania infantum for which dogs are the main reservoirs. A vaccine against canine visceral leishmaniasis (CVL) could be an important tool in the control of human and CVL by reducing the infection pressure of L. infantum. Despite the CVL vaccine available on the market, the Brazilian Ministry of Health did not implement the use of it in their control programs. In this sense, there is an urgent need to develop more efficient vaccines. In this study, the association between two polymeric nanoformulations, (poly (D, L-lactic) acid (PLA) polymer) loading Leishmania amazonensis antigens, was evaluated as a potential immunobiological agent against VL using golden hamsters as an experimental model. The results indicated that no significant adverse reactions were observed in animals vaccinated with LAPSmP. LAPSmP presented similar levels of total anti-Leishmania IgG as compared to LAPSmG. The LAPSmP and LAPSmG groups showed an intense reduction in liver and spleen parasitic load by qPCR. The LAPSmP and LAPSmG vaccines showed exceptional results, indicating that they may be promising candidates as a VL vaccine.