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https://hdl.handle.net/20.500.12955/1143
Título : | Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon |
Autor : | Tauchen, Jan Bortl, Ludvik Huml, Lukas Miksatkova, Petra Doskocil, Ivo Marsik, Petr Panduro Villegas, Pablo Pedro Bendezu Flores, Ymber Van Damme, Patrick Lojka, Bohdan Havlik, Jaroslav Lapcik, Oldrich Kokoska, Ladislav |
Fecha de publicación : | 14-jun-2016 |
Resumen : | Among 23 extracts of medicinal and edible plants tested, Mauritia flexuosa L.f., Arecaceae, showed significant antioxidant ability (DPPH and ORAC = 1062.9 and 645.9 ± 51.4 μg TE/mg extract, respectively), while Annona montana Macfad., Annonaceae, demonstrated the most promising anti-proliferative effect (IC50 for Hep-G2 and HT-29 = 2.7 and 9.0 μg/ml, respectively). However, combinatory antioxidant/anti-proliferative effect was only detected in Oenocarpus bataua Mart., Arecaceae (DPPH = 903.8 and ORAC = 1024 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 102.6 and 38.8 μg/ml, respectively) and Inga edulis Mart., Fabaceae (DPPH = 337.0 and ORAC = 795.7 μg TE/mg extract; IC50 for Hep-G2 and HT-29 at 36.3 and 57.9 μg/ml, respectively). Phenolic content was positively correlated with antioxidant potential, however not with anti-proliferative effect. None of these extracts possessed toxicity towards normal foetal lung cells, suggesting their possible use in development of novel plant-based agents with preventive and/or therapeutic action against oxidative stress-related diseases. |
Palabras clave : | Antioxidant Anticarcinogenic Phenolic compounds Plant extracts |
Editorial : | El Sevier |
Citación : | Tauchen, J.; Bortl, L.; Huml, L.; Miksatkova, P.; Doskocil, I.; Marsik, P.; Panduro, P.; Bendezu, Y.; Van Damme, P.; Lojka, B.; Havlik, J.; Lapcik, O.; Kokoska, L. (2016). Phenolic composition, antioxidant and anti-proliferative activities of edible and medicinal plants from the Peruvian Amazon. Revista Brasileira de Farmacognosia Volume 26, Issue 6, Pages 728-737. doi: 10.1016/j.bjp.2016.03.016 |
URI : | http://repositorio.inia.gob.pe/handle/20.500.12955/1143 |
metadata.dc.identifier.doi: | http://dx.doi.org/10.1016/j.bjp.2016.03.016 |
metadata.dc.subject.ocde: | Biotecnología agrícola, Biotecnología alimentaria |
Aparece en las colecciones: | Artículos científicos |
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Tauchen-et-el_2016_Antioxidant_Anti-proliferative.pdf | 552,08 kB | Adobe PDF | Visualizar/Abrir |
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